- Report finds 78% choose OpenAI models, but many are split across multiple families and generations
- Anthropic started to pick up in mid-2025, with 75% using Sonnet/Opus 4.5
- M365 Copilot is still a firm favorite, far surpassing Gemini for Workspace
ChatGPT producer OpenAI remains the most popular model provider chosen by enterprises, according to new data from Global 2000 company CIOs, with nearly four in five (78%) choosing OpenAI’s models for production.
However, models from rival companies Anthropic and Google are gaining popularity, and Anthropic uptake is increasing from mid-2025.
But more importantly, data from venture capitalist giant Andreessen Horowitz (a16z) reveals that specific use cases will play the most important role in the model decision.
OpenAI’s popularity will soon be challenged by Anthropic
CIOs prefer OpenAI for general chat, knowledge management and customer support, but Anthropic is gaining popularity for its better performance in software development and data analytics. CIOs noted that Gemini works well quite broadly, but it lags in some cases of coding.
And like hybrid and multicloud models, enterprises are moving away from supporting a single provider, with 81% now using three or more model families in testing or production stages. This has already increased from 68% in less than a year.
As for Anthropic, it’s clear that its newer models are more of a hit than previous generation models. Three out of four Anthropic customers had Sonnet 4.5 or Opus 4.5 in production, compared to OpenAI, whose customers still use many earlier models. Less than half (46%) used GPT-5.2.
Part of this trend can be attributed to modeling capabilities, with companies claiming faster time to value, less rapid construction and greater confidence.
a16z also highlighted the prevalence of Microsoft 365 Copilot in the enterprise world, which is far more popular than Google Gemini for Workspace.
Looking ahead, most companies still measure AI ROI on productivity and cost savings, but employee and customer satisfaction/retention are starting to gain traction. Four out of five of the Global 2000 companies expect to break even or deliver a higher ROI.
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