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Bookies note that because information is king when it comes to the NFL Draft, it is difficult for them to win the day.
This also means that analysts and fans who have been paying close attention, or have an inside scoop, may be in a good position when betting on how many players from each major conference will be selected in Round 1.
Let’s take a look at these odds at Draftking’s Sportsbook starting April 22nd.
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2026 NFL Draft
A total of ten major players selected in the first round
Under 11.5: -165 (bet $10 to win $16.06 total)
Over 11.5: +125 (bet $10 to win $22.50 total)
Total number of ACC players selected in the first round
Under 6.5: -700 (bet $10 to win $11.43 total)
Over 6.5: +400 (bet $10 to win $50 total)
What you need to know: Based on the odds, the ACC could only get a handful of players off the board Thursday night. And there is also some analysis that supports these odds. In his latest mock draft, FOX Sports lead college football analyst Joel Klatt has five players from the ACC going in the first round. On his list from Miami are Francis Mauigoa (projected No. 4 pick), Rueben Bain Jr. (No. 12) and Akheem Mesidor (No. 15). Also from the ACC, he expects two Clemson Tigers — TJ Parker and Blake Miller — to come off the board at 22 and 23, respectively.
A total of 12 major players selected in the first round
Under 5.5: -270 (bet $10 to win $13.70 total)
Over 5.5: +190 (bet $10 to win $29 total)
Total number of SEC players selected in the first round
Under 8.5: -185 (bet $10 to win $15.41 total)
Over 8.5: +140 (bet $10 to win $24 total)
What you need to know: In the 2025 NFL Draft, 15 players from the SEC were selected in Round 1. Will the conference where “it just means more” continue its first-round reign in 2026? According to FOX Sports NFL analyst Bucky Brooks, players may want to keep an eye on Over. He predicts nine players from the SEC will hear their names called on Thursday. That includes Mansoor Delane (LSU), Monroe Freeling (Georgia), Jermod McCoy (Tennessee), Chase Bisontis (Texas A&M), Kadyn Proctor (Alabama), Keldric Faulk (Auburn), Cashius Howell (Texas A&M), Colton Hood (Tennessee) and KC Concepción (Texas A&M).
